Does digital CBT for insomnia hold up over the long term?
Yes, the evidence is strongest here. Multiple randomized trials show that digital CBT for insomnia (dCBT-I) produces improvements that last 6 to 12 months after treatment. In one large trial with 238 participants, dCBT-I led to a large reduction in insomnia severity at 8 weeks, and those gains were sustained at both 6- and 12-month follow-ups [10]. Another study using a smartphone app in China found that participants who received dCBT-I had significantly lower insomnia scores than a sleep-education group at 3 months and maintained better sleep efficiency (87.5% vs. 78.1%) and longer total sleep time at 6 months [4].
A retrospective study of over 4,000 patients compared dCBT-I to medication and found that dCBT-I was more effective than medication alone at 6 months, though the authors noted that benefits 'fluctuated' after the first 3 months, suggesting that some people may need a booster or combination approach [5]. Importantly, a pilot study found that a second course of dCBT-I helped 62.5% of patients who hadn't fully responded to the first course achieve remission at 3-month follow-up [13]. This suggests that for insomnia, long-term success is achievable, but it may require persistence or tailored support for those who don't improve initially.
What about depression, OCD, smoking, and other conditions?
For depression, a comprehensive meta-analysis of 15 randomized controlled trials (over 2,000 participants) found that internet-based CBT (iCBT) self-help programs were superior to control conditions at follow-up points ranging from 8 weeks to over a year, with a medium effect size [3][11]. Importantly, within the iCBT groups, symptoms continued to improve slightly from post-treatment to follow-up, meaning the benefits didn't just hold—they got a little better over time [3][11].
For obsessive-compulsive disorder (OCD), a 24-month follow-up of guided iCBT found that remission rates actually increased from 48% right after treatment to 76% at 24 months, suggesting that skills learned during therapy continue to pay off [1]. For smoking cessation, a randomized trial of a clinician-assisted digital CBT program found that 22.6% of participants remained abstinent at 52 weeks, compared to 13.2% in a brief-advice control group—a 71% higher likelihood of staying quit [7]. For atopic dermatitis (eczema), a 12-week internet-delivered CBT program produced moderate-to-large reductions in symptoms that were sustained at 12-month follow-up [6].
However, the evidence is not uniformly strong. A systematic review of digital CBT for obesity found that while initial weight loss was promising (up to -7 kg), user engagement dropped sharply over time, and long-term results were best when digital tools were combined with occasional human coaching [9]. Similarly, a study of digital CBT for chronic pain in primary care found only 'modest but sustained' improvements in pain impact at 12 months, and it did not reduce opioid use [12].
What predicts whether someone will benefit long-term?
Not everyone responds equally, and the research points to a few key factors. First, people with more severe symptoms at the start may need extra support: a study of older adults with insomnia found that those with higher baseline insomnia severity were significantly less likely to make sufficient progress after two months of dCBT-I [8]. Second, engagement matters—participants who completed more of the digital program saw greater improvements [2][9]. For example, in a trial for Black women with insomnia, those who completed the full digital program had a 10.4-point reduction in insomnia severity, compared to 6.2 points for non-completers [2].
Third, the type of delivery influences long-term durability. Blended models—digital programs with some human guidance (e.g., brief therapist check-ins or group sessions)—tend to show stronger and more sustained effects than fully automated programs [1][7][9]. For instance, the OCD study that showed 76% remission at 24 months used guided iCBT with therapist support [1], and the smoking cessation study that found 52-week benefits included clinician assistance [7]. Finally, cultural tailoring can improve engagement: a version of dCBT-I adapted for Black women had a 78% completion rate versus 65% for the standard version, and completion was linked to better outcomes [2].
About These Sources
This answer is built on 13 peer-reviewed studies — published from 2021 to 2026, 4 from 2024 or later, 10 in Q1 journals, collectively cited 378 times — selected as the most relevant from 15 studies that passed quality screening, drawn from 65 papers retrieved from a database of over 500 million.
Sources used in this answer
Long-term effectiveness and cost-effectiveness of guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: 24-month follow-up
In a 24-month follow-up of guided iCBT for OCD, remission rates increased from 48% post-treatment to 76% at 24 months, demonstrating sustained long-term effectiveness [1].
Effect of Culturally Tailored, Internet-Delivered Cognitive Behavioral Therapy for Insomnia in Black Women
In a randomized trial of 333 Black women, both standard and culturally tailored digital CBT-I significantly reduced insomnia severity at 6 months, with the tailored version achieving higher completion rates (78% vs. 65%) [2].
Long-Term Efficacy of Internet-Based Cognitive Behavioral Therapy Self-Help Programs for Adults With Depression: Systematic Review and Meta-Analysis of Randomized Controlled Trials
A meta-analysis of 15 RCTs found that iCBT for depression maintained a medium effect size (SMD -0.43) over control conditions at follow-up, with symptoms continuing to improve slightly after treatment ended [3].
Digital Cognitive Behavioral Therapy for Insomnia Using a Smartphone Application in China
A Chinese smartphone-based dCBT-I trial (82 participants) showed significantly lower insomnia scores at 3 months and better sleep efficiency (87.5% vs. 78.1%) at 6 months compared to sleep education [4].
Comparative Effectiveness of Digital Cognitive Behavioral Therapy vs Medication Therapy Among Patients With Insomnia
In a retrospective study of 4,052 patients, dCBT-I was more effective than medication alone at 6 months (PSQI reduction from 13.5 to 7.2 vs. 12.9 to 8.9), though benefits fluctuated after 3 months [5].
Internet-Delivered Cognitive Behavior Therapy for Atopic Dermatitis
Internet-delivered CBT for atopic dermatitis (102 adults) produced moderate-to-large symptom reductions (d=0.75) that were sustained at 12-month follow-up [6].
Long-Term Effectiveness of a Clinician-Assisted Digital Cognitive Behavioral Therapy Intervention for Smoking Cessation: Secondary Outcomes From a Randomized Controlled Trial
A randomized trial of 556 smokers found that clinician-assisted digital CBT led to 22.6% abstinence at 52 weeks vs. 13.2% for brief advice, a 71% higher likelihood of staying quit [7].
1063 Predictors of Insufficient Treatment Response to Digital CBT-I: Results from the RESTING Study
Among 101 older adults triaged to dCBT-I, those with higher baseline insomnia severity were significantly less likely to make sufficient progress after 2 months (p=.002) [8].
A SYSTEMATIC REVIEW OF THE EFFICACY OF DIGITAL THERAPEUTICS (DTx) UTILIZING COGNITIVE BEHAVIORAL THERAPY (CBT) FOR LONG-TERM OBESITY MANAGEMENT IN ADULTS
A systematic review of 10 RCTs found that CBT-based digital therapeutics for obesity produced clinically significant weight loss (up to -7 kg), but user engagement declined over time, and blended models with human coaching showed better long-term results [10].
The clinical effects of digital cognitive behavioral therapy for insomnia in a heterogenous study sample: results from a randomized controlled trial
A German RCT of 238 participants found that dCBT-I produced large reductions in insomnia severity (d=-2.08) that were sustained at 6- and 12-month follow-ups [11].
Long-Term Efficacy of Internet-Based Cognitive Behavioral Therapy Self-Help Programs for Adults With Depression: Systematic Review and Meta-Analysis of Randomized Controlled Trials (Preprint)
This meta-analysis (same as paper 3) confirmed that iCBT for depression outperformed controls at follow-up (SMD -0.43) and that within-group improvements continued after treatment [12].
A Primary Care–Based Cognitive Behavioral Therapy Intervention for Long-Term Opioid Users With Chronic Pain
A primary care-based group CBT for chronic pain (850 patients) produced modest but sustained reductions in pain impact at 12 months but did not reduce opioid use [13].
Efficacy of repeated self-guided digital cognitive behavioral therapy for chronic insomnia: A pilot open-label study following a previous RCT
A pilot study found that a second course of dCBT-I helped 62.5% of initial non-responders achieve remission at 3-month follow-up, suggesting booster sessions can help [14].
